Reflection: Real World Applications Two Stories + Two Tools= Understanding & Predicting Huntington's Disease! - Section 2: Explain


        Real world applications are miracle workers in the classroom when highly complicated content stands between the instructor and student comprehension. In this part of the lesson, I knew that in order for students to understand how and why the faulty HD gene's protein product leads to cell suicide that it would take me explaining the micro-physiology of the spiny cell.  In the effort to successfully communicate this, I developed an analogy that compares the demise of the cell to a poorly run household. (see student notes from this analogy attached). As a result, students were able to more effectively communicate the biochemical and physiological underpinnings of the disease in their notes, comic strips and among conversations with their peers. One young lady was so intrigued with the analogy that she spent her lunch time in my classroom explaining how Huntington's Disease manifests at the cellular and biochemical level to her close friends! 

  Real World Applications: Using Analogies to Unpack Complicated Micro-Physiology
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Two Stories + Two Tools= Understanding & Predicting Huntington's Disease!

Unit 7: Genetics and the Brain
Lesson 5 of 6

Objective: Students will gather and synthesize information from case studies and biotechnological tools to predict if mutated genes effects the proteins produced in neurons (eg. Huntington's Disease).

Big Idea: Biotechnology enhances our ability to detect and prepare for Huntington's Disease prior to its onset!

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